2014 - 2014
Whole genome sequencing of <i>Campylobacter jejuni</i>, a new diagnostic tool for studies of <i>Campylobacter</i> from animal and environmental sources and from humans
Genotyping of C. jejuni isolates by MLST (Multi locus sequence typing) has shown that certain MLST types are common among animals and environmental sources and among humans. Such common types will be analysed by PFGE (Pulsed field gel electrophoresis) and whole genome sequencing in order to study diversity within MLST types. PFGE gives a higher resolution compared to MLST and if certain clones are detected they will be studied by whole genome sequencing. The sequencing will give detailed information about phylogeny and presence of virulence associated genes. Whole genome sequencing will also be used for finding new biomarkers, useful for development of diagnostics for the detection and identification of virulence associated characteristics in Campylobacter.