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Lijo John
Titel :Forskare, Dr. rer. nat./PhD
Forskningsområde :Virus-värd-interaktioner, mRNA-vaccin, antivirala medel
Mina nuvarande projekt är inriktade på haploida genetiska undersökningar (där celler med enkel kromosomuppsättning utnyttjas) som genererar information om värdfaktorer som är avgörande för virus som Bluetongue, SARS-CoV-2 och Marburg-virus. Jag deltar också i ett projekt som utvecklar RNA-vaccin mot kring Krim-Kongo blödarfebervirus (CCHFV).
Aktuella projekt
Alla projekt
För ytterligare SVA-projekt, sök här:
Publikationer
A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection (2021)
Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46 (2021)
Human AdV-20-42-42, a promising novel adenoviral vector for gene therapy and vaccine product development (2021)
Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56 (2018)
Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1 (2014)
Hepatitis E virus ORF2 protein activates the pro-apoptotic gene CHOP and anti-apoptotic heat shock proteins (2011)
Chikungunya virus capsid protein contains nuclear import and export signals (2013)
Converging evidence of mitochondrial dysfunction in a yeast model of homocysteine metabolism imbalance (2011)
Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast (2006)
Cigarette smoke extract induces changes in growth and gene expression of Saccharomyces cerevisiae (2005)