Sequencing technologies and PCR based detection
We are using new sequencing technologies both to support the development of better assays and to directly interrogate whole populations of bacteria, viruses and parasites in ways that have not been possible before. Advances in sequencing as well as other fields such as sample preparation and target molecule enrichment techniques will allow us to simultaneously detect multiple pathogens in host materials. We are also working with development of PCR based detction using different techniques, for example multiplex PCR, suspension PCR and bead-based PCR (Luminex).
Mass spectrometric techniques
In the field of serology, advances in nanotechnology and microfluidics will open up for new diagnostic platforms. Mass spectrometry has been used at SVA for many years for the identification and quantification of small molecules like drugs and doping compounds. Recently, however, mass spectrometric techniques have been introduced into the fields of toxin detection and identification of bacteria.
Rapid and accurate diagnosis of diseases
We also strive to integrate advances in biochemistry and proteomics, a combination which offers enormous potential for the rapid and accurate diagnosis of viral, microbial, genetic and metabolic diseases.
High-throughput sequencing for detection and typing of pathogens
Robert Söderlund, researcher
Mikael Leijon, researcher
Molecular based detection of pathogens
Mats Isaksson, research engineer
Mass spectrometry as a diagnostic tool
Mikael Hedeland, associate professor