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Foto: Göran Ekeberg/AddLight Ali Mirazimi Forskare, adjungerad professor Inst. för Laboratoriemedicin ali.mirazimi@sva.se 070-367 25 73

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logo Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.Hoffmann D, Mereiter S, Jin Oh Y, Monteil V, Elder E, Zhu R, Canena D, Hain L, Laurent E, Grünwald-Gruber C, Klausberger M, Jonsson G, Kellner MJ, Novatchkova M, Ticevic M, Chabloz A, Wirnsberger G, Hagelkruys A, Altmann F, Mach L, Stadlmann J, Oostenbrink C, Mirazimi A, Hinterdorfer P, Penninger JM.EMBO J. 2021 Oct 1;40(19):e108375. 5. Epub 2021 Aug 23. logo A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection.Miller A, Leach A, Thomas J, McAndrew C, Bentley E, Mattiuzzo G, John L, Mirazimi A, Harris G, Gamage N, Carr S, Ali H, Van Montfort R, Rabbitts T.Sci Rep. 2021 May 19;11(1):10617. logo Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana.Castilho A, Schwestka J, Kienzl NF, Vavra U, Grünwald-Gruber C, Izadi S, Hiremath C, Niederhöfer J, Laurent E, Monteil V, Mirazimi A, Wirnsberger G, Stadlmann J, Stöger E, Mach L, Strasser R.Biotechnol J. 2021 Jun;16(6):e2000566. Epub 2021 Feb 12. logo Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.Monteil V, Dyczynski M, Lauschke VM, Kwon H, Wirnsberger G, Youhanna S, Zhang H, Slutsky AS, Hurtado Del Pozo C, Horn M, Montserrat N, Penninger JM, Mirazimi A.EMBO Mol Med. 2021 Jan 11;13(1):e13426. . Epub 2020 Dec 14. logo Human recombinant soluble ACE2 in severe COVID-19.Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM.Lancet Respir Med. 2020 Nov;8(11):1154-1158. Epub 2020 Sep 24. logo Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.Monteil V, Kwon H, Prado P, Hagelkrüys A, Wimmer RA, Stahl M, Leopoldi A, Garreta E, Hurtado Del Pozo C, Prosper F, Romero JP, Wirnsberger G, Zhang H, Slutsky AS, Conder R, Montserrat N, Mirazimi A, Penninger JM.Cell. 2020 May 14;181(4):905-913.e7. Epub 2020 Apr 24.